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Treatment of Fibrocystic Mastopathy by an Antiestrogen, Tamoxifen
Author(s) -
Shaaban Mamdouh M.,
Morad Farouk,
Hassan AbdElRazik R.
Publication year - 1980
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1002/j.1879-3479.1980.tb00512.x
Subject(s) - medicine , antiestrogen , tamoxifen , tenderness , serous fluid , nipple discharge , surgery , gynecology , mammography , cancer , breast cancer
For three successive months, 31 patients with fibrocystic mastopathy were treated with an antiestrogen, tamoxifen. As a result, the pain subsided in all but one of them. Disappearance or marked amelioration was also noticed in the objective signs of tenderness, diffuse induration and ill‐defined tender lumps. The least‐affected signs were serous discharge from the nipple and well‐defined tumor masses. Side effects to treatment were minimal, and benefits persisted for three months after the end of therapy in two thirds of the patients.