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Reduction of Menstrual Blood Loss by Naproxen in Intrauterine Contraceptive Device Users
Author(s) -
Davies A. J.
Publication year - 1980
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1002/j.1879-3479.1980.tb00298.x
Subject(s) - medicine , intrauterine device , naproxen , reduction (mathematics) , blood loss , menstruation , menstrual bleeding , obstetrics , gynecology , family planning , population , research methodology , surgery , alternative medicine , environmental health , geometry , mathematics , pathology
Eleven patients with objective evidence of menorrhagia (>80 ml menstrual blood loss for two cycles) while fitted with an IUD were treated during three consecutive menstruations with the prostaglandin synthetase inhibitor naproxen. Menstrual blood loss was significantly reduced (p < 0.001) from a pretreatment value of 131 ± 12 ml to 88 ± 9 ml on naproxen therapy. In the cycle following naproxen therapy, menstrual blood loss returned to the pretreatment level of 129 ± 10 ml. Continued IUD usage was made more acceptable by naproxen therapy.