Premium
Tumorigenic Aspects
Author(s) -
Kirk Mary Ellen
Publication year - 1979
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1002/j.1879-3479.1979.tb00952.x
Subject(s) - medicine , focal nodular hyperplasia , hamartoma , adenoma , differential diagnosis , hyperplasia , pathology , uterus , liver cell , gynecology , hepatocellular carcinoma
Kirk ME (Depts of Pathology, McGill University and The Montreal General Hospital, Montreal, Canada). Tumorigenic aspects. Int J Gynaecol Obstet 16: 473–478, 1979 This report presents a review of tumors, except those of pituitary, that have been reported to occur in women taking combined oral contraceptive preparations. Pathologic features, both gross and microscopic, and differential diagnosis are emphasized. Particular attention is given to tumors of the liver: focal nodular hyperplasia (hepatic hamartoma) and liver cell adenoma (benign hepatoma). The characteristic features of these usually distinctive lesions are illustrated, and an attempt is made to evaluate the significance of each with respect to oral contraceptives. Tumorigenic aspects relating to the uterus and the breast are briefly discussed.