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Galactorrhea and the Defective Luteal Phase of the Menstrual Cycle
Author(s) -
Mahgoub S. El
Publication year - 1978
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1002/j.1879-3479.1978.tb00411.x
Subject(s) - medicine , luteal phase , galactorrhea , menstrual cycle , follicular phase , prolactin , hormone
Twelve patients with primary infertility due to a defective luteal phase associated with hyperprolactinemia and galactorrhea are reported. All were treated with 2‐bromoergocryptine. During the first cycle of therapy, the serum prolactin level decreased in all cases, and galactorrhea disappeared during the second cycle of therapy. Seven women responded to 2‐bromoergocryptine, as was reflected in their endometrial biopsies. The remaining five were given clomiphene citrate on the second and sixth days of the next 2‐bromoergocryptine cycle. Three of these patients responded favorably to this combined therapy. Six pregnancies were reported during therapy. The results of follow‐up after labor or abortion suggested that these cases represent a latent stage of the amenorrhea‐galactorrhea syndrome.