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Plasma Estradiol as a Predictor of Preterm Labor
Author(s) -
TambyRaja R. L.,
Lun K. C.
Publication year - 1978
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1002/j.1879-3479.1977.tb00750.x
Subject(s) - medicine , gestation , pregnancy , obstetrics , linear regression , preterm labor , endocrinology , statistics , genetics , mathematics , biology
Studies have shown a rapid rise of plasma estradiol‐17 β in the maternal circulation before the occurrence of preterm labor. We have attempted to perform a linear regression analysis of the data from normal pregnancies and to set up a 95% upper prediction limit for the normal range of the estradiol level for each week of gestation. The prediction limits were reasonably good, with only five (13%) false negatives. False negatives tend to occur only in late pregnancy.