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Serum Naphthylamidase Isoenzymes during Hormonal Treatment
Author(s) -
Beckman G.,
Beckman L.,
Damber M.G.,
Helgason S.,
Lundgren E.,
Schoultz B.
Publication year - 1976
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1002/j.1879-3479.1976.tb00106.x
Subject(s) - medicine , isozyme , hormone , pharmacology , biochemistry , enzyme , chemistry
Beckman, G., Beckman, L., Damber, M.‐G., Helgason, S., Lundgren, E. and von Schoultz, B. (Departments of Medical Genetics, Obstetrics and Gynaecology, and Pathology, University of Umeå, Umeå, Sweden). Serum naphthylamidase isoenzymes during hormonal treatment. Electrophoretic and quantitative studies . Int J Gynaecol Obstet 14 : 550–552, 1976. Alterations in serum naphthylamidase isoenzymes were studied by electrophoretic and quantitative methods in women treated with oral contraceptives and women treated with naturally occurring conjugated estrogens for climacteric symptoms. In women treated with oral contraceptives the appearance of extra isoenzyme components was accompanied by a distinct and significant increase in the total serum naphthylamidase activity, whereas in treatment with conjugated estrogens no such increase was found. The result suggests that combined oral contraceptives and natural estrogens affect the serum naphthylamidase pattern in different ways.