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Plasma Protein Changes Induced by Acute Inflammation of the Fallopian Tubes
Author(s) -
Jacobson L.,
Laurell C.B.,
Gennser G.,
Marholev K.
Publication year - 1975
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1002/j.1879-3479.1975.tb00061.x
Subject(s) - medicine , salpingitis , pelvic inflammatory disease , acute phase protein , orosomucoid , inflammation , laparoscopy , c reactive protein , gastroenterology , gynecology , surgery , glycoprotein , microbiology and biotechnology , biology
Jacobson, L., Laurell, C.‐B., Gennser, G. and Mar‐holev, K. (Depts, of Obstetrics & Gynaecology and of Clinical Chemistry, University of Lund, Malmö General Hospital, Malmö, Sweden). Plasma protein changes induced by acute inflammation of the Fallopian tubes . Int J Gynaecol Obstet 13 : 249–256, 1975. In 72 patients, subjected to laparoscopy on the pre‐explorative, clinical diagnosis of acute salpingitis, the inflammatory plasma protein response was analysed and correlated with the visual findings. Of the “acute phase reactants” determined, antichymotrypsin, orosomucoid, and C‐reactive protein (CRP) provided diagnostic guidance significantly superior to that given by conventional clinical symptoms and signs in this disease. The antichymotrypsin plasma concentration showed the closest correlation with the degree of tubal inflammatory reaction as found at laparoscopy. Determination of these plasma proteins should be considered an important aid in the clinical diagnosis of acute salpingitis.