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Suspected Chromium Picolinate‐Induced Rhabdomyolysis
Author(s) -
Martin William R.,
Fuller Robert E.
Publication year - 1998
Publication title -
pharmacotherapy: the journal of human pharmacology and drug therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.227
H-Index - 109
eISSN - 1875-9114
pISSN - 0277-0008
DOI - 10.1002/j.1875-9114.1998.tb03910.x
Subject(s) - rhabdomyolysis , medicine , sepsis , muscle disease , chromium , anesthesia , disease , chemistry , organic chemistry
Rhabdomyolysis results from skeletal muscle injury and release of muscle cell contents into plasma. A number of etiologic factors have been reported for the condition, including strenuous exercise, weight lifting, trauma, seizure, sepsis, and alcohol and drug abuse. Hundreds of drugs also reportedly cause rhabdomyolysis. A 24‐year‐old body builder developed the disease after ingesting 1200 μg of chromium picolinate (6–24 times the daily recommended allowance of 50–200 μg) over 48 hours. We believe this to be the first reported case of chromium‐induced rhabdomyolysis.