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Treatment of Septic Shock with Immunotherapy
Author(s) -
Smith Adrienne L.
Publication year - 1998
Publication title -
pharmacotherapy: the journal of human pharmacology and drug therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.227
H-Index - 109
eISSN - 1875-9114
pISSN - 0277-0008
DOI - 10.1002/j.1875-9114.1998.tb03119.x
Subject(s) - septic shock , sepsis , medicine , intensive care medicine , immunotherapy , critically ill , shock (circulatory) , mortality rate , antibiotics , cause of death , clinical trial , immunology , immune system , disease , biology , microbiology and biotechnology
Sepsis is the thirteenth leading cause of death in the United States. Despite increased knowledge about its pathophysiology, availability of powerful antibiotics, and advanced diagnostic and monitoring techniques, mortality rates have not changed significantly over the past 30 years. Immunotherapy may improve outcome in the critically ill with sepsis, although trial results have been disappointing to date.