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Anaphylactoid Reaction With Suramin
Author(s) -
Thibault Alain,
Figg William D.,
Cooper Michael R.,
Prindiville Sheila A.,
Sartor A. Oliver,
Headlee Donna J.,
Myers Charles E.
Publication year - 1993
Publication title -
pharmacotherapy: the journal of human pharmacology and drug therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.227
H-Index - 109
eISSN - 1875-9114
pISSN - 0277-0008
DOI - 10.1002/j.1875-9114.1993.tb02774.x
Subject(s) - suramin , diphenhydramine , anaphylaxis , medicine , epinephrine , allergic reaction , drug , hypersensitivity reaction , pharmacology , anesthesia , allergy , immunology , histamine , receptor
Suramin, a drug used to treat parasitic diseases, is currently being investigated as a treatment for metastatic prostate cancer. A 73–year‐old man had an anaphylactoid reaction following the first dose of suramin. It was treated successfully with epinephrine, diphenhydramine, and hydrocortisone. Investigators should be aware of the possibility of such a reaction with parenteral administration of this drug.