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Review of Drug‐Induced Acute Interstitial Nephritis
Author(s) -
Murray Kim M.,
Keane William R.
Publication year - 1992
Publication title -
pharmacotherapy: the journal of human pharmacology and drug therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.227
H-Index - 109
eISSN - 1875-9114
pISSN - 0277-0008
DOI - 10.1002/j.1875-9114.1992.tb04490.x
Subject(s) - medicine , nonsteroidal , drug , interstitial nephritis , nephritis , antibiotics , intensive care medicine , antiinflammatory drug , pharmacology , kidney , chemistry , biochemistry
Drug‐induced acute interstitial nephritis (AIN) is a rare, potentially correctable cause of acute renal failure. Early recognition and appropriate therapy are essential to its management. Several drugs have been associated with the development of AIN, including antibiotics and nonsteroidal antiinflammatory agents, all with characteristic mechanisms of toxicity.