Premium
Surgical Antimicrobial Prophylaxis: Principles and Guidelines
Author(s) -
Burnakis Thomas G.
Publication year - 1984
Publication title -
pharmacotherapy: the journal of human pharmacology and drug therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.227
H-Index - 109
eISSN - 1875-9114
pISSN - 0277-0008
DOI - 10.1002/j.1875-9114.1984.tb03373.x
Subject(s) - medicine , intensive care medicine , antibiotic prophylaxis , antimicrobial , cephalosporin , antibiotics , medline , surgery , chemistry , organic chemistry , political science , law , microbiology and biotechnology , biology
Antimicrobial prophylaxis for surgical procedures is an area that is recognized as being subject to individual clinical variations. This review gives practitioners some basic principles of rational prophylaxis as defined by the medical literature. In addition, this literature is evaluated and condensed to provide clinicians with guidelines for particular procedures: obstetric, gynecologic, gastric, biliary, colonic, urologic, cardiac, thoracic, vascular, orthopedic and head and neck. Each section concludes with recommendations for the clinically most accepted prophylactic regimens. Antibiotics discussed include not only the older agents, but where good information exists, the newer cephalosporins. The suggested regimens consider efficacy, safety and cost as determinants in rational prescribing. Although research into even shorter, and perhaps more cost‐effective, regimens continues, this compilation lists state‐of‐the‐art recommendations.