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Fundamentals of Present‐Day Mass Spectrometry
Author(s) -
Costello Catherine E.
Publication year - 1986
Publication title -
the journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.92
H-Index - 116
eISSN - 1552-4604
pISSN - 0091-2700
DOI - 10.1002/j.1552-4604.1986.tb03546.x
Subject(s) - mass spectrometry , field (mathematics) , reliability (semiconductor) , biochemical engineering , sensitivity (control systems) , chemistry , data science , computer science , chromatography , engineering , mathematics , physics , power (physics) , quantum mechanics , electronic engineering , pure mathematics
Mass spectral analysis offers much to the field of clinical pharmacology: specificity, sensitivity, reliability, and potential for the structural determination of unknown compounds, even when they are present at very low concentrations as part of complex mixtures. In order to employ mass spectrometry effectively, the researcher or analyst must acquire an understanding of the fundamental processes involved in the technique and some overview of the strengths and limitations of the different options now available. This brief summary is presented as an introduction to the field and should provide the impetus for further reading by the interested investigator.