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Comparison of Two Sustained‐Release Theophylline Preparations in Adult Patients With Obstructive Airways Disease
Author(s) -
Harkaway Paul S.,
Conlon Paul F.,
Hirsh John D.,
Allen William T.
Publication year - 1985
Publication title -
the journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.92
H-Index - 116
eISSN - 1552-4604
pISSN - 0091-2700
DOI - 10.1002/j.1552-4604.1985.tb02874.x
Subject(s) - pharmacy , medicine , theophylline , philosophy , classics , history , family medicine
The bioavailability profiles of two sustained-release oral theophylline preparations, Respbid and Theo-Dur, were compared in 19 adults with obstructive airways disease. Intravenous aminophylline was used as the reference standard. No significant differences were detected in fraction absorbed, peak-trough fluctuations, or time to peak concentrations.