Premium
The Respiratory Effects of Dezocine and Pentazocine in Man
Author(s) -
WUEST HANS PETER,
BELLVILLE J. WELDON
Publication year - 1979
Publication title -
the journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.92
H-Index - 116
eISSN - 1552-4604
pISSN - 0091-2700
DOI - 10.1002/j.1552-4604.1979.tb01653.x
Subject(s) - pentazocine , dezocine , respiratory system , anesthesia , medicine , depressant , respiration , pharmacology , analgesic , anatomy
The respiratory effects of dezocine and pentazocine were studied in five volunteers. Based on their effects over a 3-hour period, it was found that dezocine was 8.6 times as potent as pentazocine in terms of their respiratory depressant effects. The clinical significance of these findings remains to be determined.