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A Controlled Comparison of Doxepin h.s. and Doxepin q.i.d.
Author(s) -
MENDELS J.,
SCHLESS A.
Publication year - 1975
Publication title -
the journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.92
H-Index - 116
eISSN - 1552-4604
pISSN - 0091-2700
DOI - 10.1002/j.1552-4604.1975.tb01477.x
Subject(s) - doxepin , pharmacology , medicine
A controlled double-blind study of 40 depressed psychiatric outpatients who received doxepin either q.i.d. or h.s. showed that doxepin may be administered h.s. without loss of efficacy or increase in side effects. The patients who received doxepin h.s. felt significantly better rested in the morning than the patients who received doxepin in divided doses.