Premium
Deaths from Drugs. An Analysis of Drug‐Induced Deaths Reported to the Swedish Adverse Drug Reaction Committee During a Five‐Year Period (1966–1970)
Author(s) -
BÖTTIGER L. E.,
NORDLANDER M.,
STRANDBERG I.,
WESTERHOLM B.
Publication year - 1974
Publication title -
the journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.92
H-Index - 116
eISSN - 1552-4604
pISSN - 0091-2700
DOI - 10.1002/j.1552-4604.1974.tb02320.x
Subject(s) - welfare , medicine , family medicine , drug , adverse drug reaction , political science , pharmacology , law
An analysis of the drug-induced deaths reported to the Swedish Adverse Drug Reaction Committee during its first 5 years of existence from 1966-1970 is presented. Various classifications are given to reports of adverse drug reactions but only the first 2 classifications causal relationships probable or not excluded were included in the analysis. There were 139 such cases. In 21% of the cases antibiotics and sulfonamides were involved. Other drug classes that caused most deaths were oral contraceptives (11%) and psychotropic drugs (9%). The dominating types of reaction were hematologic (48%) thromboembolic (13%) and anaphylactic (9%). Continuous supervision of the adverse drug reaction pattern and regular analyses of various aspects of the pattern are necessary.