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PROMOTION OF PERITHECIAL INITIALS IN MONACROSPORIUM DOEDYCOIDES BY 6–METHYL PURINE
Author(s) -
Galsky Alan G.,
Monoson Herbert L.,
Pikul Frank J.,
Thompson Jeffrey S.
Publication year - 1973
Publication title -
american journal of botany
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.218
H-Index - 151
eISSN - 1537-2197
pISSN - 0002-9122
DOI - 10.1002/j.1537-2197.1973.tb05930.x
Subject(s) - biology , purine , cycloheximide , purine metabolism , rna , protein biosynthesis , biochemistry , stereochemistry , gene , chemistry , enzyme
The promotion of perithecial initials in the imperfect fungus Monacrosporium doedycoides is enhanced by the addition of the RNA synthesis inhibitor 6‐methyl purine (6‐MP). The addition of two other RNA inhibitors (8‐azaguanine and actinomycin‐D) causes the promotion of initials but not at the magnitude observed with 6‐MP. Application of a protein synthesis inhibitor (cycloheximide), a base analog (5‐fluorouracil), or an amino acid analog (p‐fluorophenyl‐alanine) are not promotive on initial formation and can be inhibitory. The apparent cause for the promotion of perithecial initials in the imperfect fungus is that sexual structures are inhibited by mRNA's synthesized by the organism and the addition of 6‐MP prohibits their synthesis.