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THIAMINE METABOLISM IN NEUROSPORA CRASSA
Author(s) -
Eberhart Bruce M.,
Tatum E. L.
Publication year - 1961
Publication title -
american journal of botany
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.218
H-Index - 151
eISSN - 1537-2197
pISSN - 0002-9122
DOI - 10.1002/j.1537-2197.1961.tb11700.x
Subject(s) - neurospora crassa , thiamine , biology , neurospora , crassa , mutant , filamentous fungus , metabolism , biochemistry , gene
E berhart , B ruce M. (Princeton U., Princeton, New Jersey), and E. L. T atum . Thiamine metabolism in Neurospora crassa , Amer. Jour. Bot. 48(8): 702–711. Illus. 1961.—Growth adaptation is a regular feature of the vegetative cycle of thi‐1 strains of Neurospora crassa but not of thi‐2 or thi‐3 strains. The adaptive growth of thi‐1 strains is paralleled by the production of cocarboxylase and carboxylase levels which are similar to those of wild‐type strains. The growth responses of thi‐1,2 and thi‐1,3 double mutant strains to thiamine indicates that the thi‐1 gene is concerned with the utilization (pyrophosphorylation) of thiamine.