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The tramtrack gene encodes a Drosophila finger protein that interacts with the ftz transcriptional regulatory region and shows a novel embryonic expression pattern.
Author(s) -
Harrison S.D.,
Travers A.A.
Publication year - 1990
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1002/j.1460-2075.1990.tb08097.x
Subject(s) - biology , embryonic stem cell , gene , regulation of gene expression , gene expression , drosophila (subgenus) , genetics , drosophila melanogaster , microbiology and biotechnology , transcriptional regulation
We have identified a Drosophila zinc‐finger protein, which binds to a number of sites in the transcriptional control regions of the pair‐rule gene fushi‐tarazu (ftz). The expression pattern of the mRNA that encodes this protein is essentially complementary to that of ftz both prior to blastoderm formation and during germband extension. We propose that the protein may function by repressing inappropriate segmentation gene transcription during embryogenesis. The gene encoding this ftz promoter‐binding protein has been named tramtrack (ttk).