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A novel, tissue‐specific, Drosophila homeobox gene.
Author(s) -
Barad M.,
Jack T.,
Chadwick R.,
McGinnis W.
Publication year - 1988
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1002/j.1460-2075.1988.tb03054.x
Subject(s) - homeobox , biology , homeobox a1 , hnf1b , homeobox protein nkx 2.5 , drosophila embryogenesis , drosophilidae , gene , genetics , cdx2 , dlx5 , imaginal disc , embryonic stem cell , drosophila (subgenus) , drosophila melanogaster , microbiology and biotechnology , gene expression
The homeobox gene family of Drosophila appears to control a variety of position‐specific patterning decisions during embryonic and imaginal development. Most of these patterning decisions determine groups of cells on the anterior‐posterior axis of the Drosophila germ band. We have isolated a novel homeobox gene from Drosophila, designated H2.0. H2.0 has the most diverged homeobox so far characterized in metazoa, and, in contrast to all previously isolated homeobox genes, H2.0 exhibits a tissue‐specific pattern of expression. The cells that accumulate transcripts for this novel gene correspond to the visceral musculature and its anlagen.