Premium
The Drosophila virilis dopa decarboxylase gene is developmentally regulated when integrated into Drosophila melanogaster.
Author(s) -
Bray S.J.,
Hirsh J.
Publication year - 1986
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1002/j.1460-2075.1986.tb04498.x
Subject(s) - drosophila melanogaster , biology , melanogaster , gene , genetics , drosophila (subgenus) , drosophila virilis , drosophilidae , aromatic l amino acid decarboxylase , enzyme , biochemistry
The dopa decarboxylase gene (Ddc) has been isolated from Drosophila virilis and introduced into the germ‐line of Drosophila melanogaster by P‐element mediated transformation. The integrated gene is induced at the correct stages during development with apparently normal tissue specificity, indicating that cis‐acting elements required for regulation are functionally conserved between the two species. A comparison of the DNA sequences from the 5′ flanking regions reveals a cluster of small (8‐16 bp) conserved sequence elements within 150 bp upstream of the RNA startpoint, a region required for normal expression of the D. melanogaster Ddc gene.