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A human T‐cell antigen receptor beta chain gene maps to chromosome 7.
Author(s) -
Collins M.K.,
Goodfellow P.N.,
Dunne M.J.,
Spurr N.K.,
Solomon E.,
Owen M.J.
Publication year - 1984
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1002/j.1460-2075.1984.tb02137.x
Subject(s) - biology , complementary dna , microbiology and biotechnology , cdna library , gene , genetics
cDNA clones which encode the human and mouse T cell antigen receptor beta chain gene have previously been isolated. We have used a mouse cDNA clone to map the chromosomal position of a human beta chain gene. Southern blot analysis of DNA prepared from somatic cell hybrids has assigned this gene to chromosome 7. The use of a hybrid containing a chromosome 7 translocation has further localised this gene to the region 7q22‐qter.