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The zeste‐white interaction: induction and genetic analysis of a novel class of zeste alleles
Author(s) -
Lifschytz Eliezer,
Green Melvin M.
Publication year - 1984
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1002/j.1460-2075.1984.tb01919.x
Subject(s) - reprint , white (mutation) , biology , library science , genealogy , genetics , history , gene , computer science , physics , astronomy
The recovery and analysis of a novel class of zeste mutations is described. z op6 and z op11 do not require two w + genes for their expression unless the z + gene is present. Analysis of genetic interactions among zeste alleles proved that z op mutations are strong antagonists of the z + gene product. z op6 is readily reverted by X‐rays or by ethylmethane sulphonate to a range of intermediate zeste alleles and thus it is considered to be an insertional mutation. We suggest that z 1 and op mutations arose as a result of insertions in a presumptive control region, and two alternative models for the structure of the zeste locus are evaluated.