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Rearrangements of the transposable mating‐type cassettes of fission yeast.
Author(s) -
Beach D.H.,
Klar A.J.
Publication year - 1984
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1002/j.1460-2075.1984.tb01855.x
Subject(s) - biology , transposable element , mating type , schizosaccharomyces , fission , genetics , yeast , schizosaccharomyces pombe , mating , dna transposable elements , evolutionary biology , saccharomyces cerevisiae , genome , gene , physics , quantum mechanics , neutron
The fission yeast, Schizosaccharomyces pombe, switches mating type every few cell divisions. Switching is controlled by the genes of the mating‐type locus, which consists of three components, mat1, mat2‐P and mat3‐M, each separated by approximately 15 kb. Copy transposition of P (Plus) or M (Minus) information from mat2‐P or mat3‐M into the expression locus mat1 mediates cell type switching. The mating‐type locus undergoes events at high frequency (10(‐2)‐10(‐6)) which stabilize one or other mating type. These events are shown to be rearrangements which result in either deletion or insertion of DNA between cassettes.