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Transcription of the Drosophila white locus and some of its mutants.
Author(s) -
Pirrotta V.,
Bröckl C.
Publication year - 1984
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1002/j.1460-2075.1984.tb01847.x
Subject(s) - biology , genetics , drosophila melanogaster , locus (genetics) , mutant , transcription (linguistics) , white (mutation) , drosophilidae , gene , microbiology and biotechnology , philosophy , linguistics
The white locus produces one major, though rare, RNA of 2.6 kb, found throughout development. Minor species of lower mol. wt. are also produced. One of these is male specific. Transcription was analysed by Northern blot hybridisation in the wild‐type and several mutants: wa, w67c23, we, wsp and zeste. These and the results of S1 mapping reveal the presence of at least four introns. One of these, a micro‐intron of 30‐50 nucleotides contains the site of copia insertion in the wa mutant.