Premium
Microtubule‐associated protein MAP2 preferentially binds to a dA/dT sequence present in mouse satellite DNA.
Author(s) -
Avila J.,
Montejo de Garcini E.,
Wandosell F.,
Villasante A.,
Sogo J.M.,
Villanueva N.
Publication year - 1983
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1002/j.1460-2075.1983.tb01574.x
Subject(s) - biology , microbiology and biotechnology
Microtubule‐associated protein MAP2 binds to the Sau96.1 restriction monomer fragment of mouse satellite DNA. This fragment is also present in a lower proportion in bulk DNA. The digestion of MAP2‐Sau96.1 fragment complex by DNase results in the protection of certain nucleotide sequences. The sequence poly(dA)4/poly(dT)4 is mainly protected against DNase digestion.