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Properties of acetylcholine receptors translated by cat muscle mRNA in Xenopus oocytes.
Author(s) -
Miledi R.,
Parker I.,
Sumikawa K.
Publication year - 1982
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1002/j.1460-2075.1982.tb01315.x
Subject(s) - biology , xenopus , acetylcholine receptor , acetylcholine , receptor , microbiology and biotechnology , messenger rna , oocyte , salientia , anatomy , genetics , endocrinology , embryo , gene
Poly(A)+ mRNA, extracted from denervated skeletal muscles of the cat, directs the synthesis of acetylcholine receptors in Xenopus laevis oocytes. The receptors are inserted in the oocyte membrane where they form acetylcholine receptor‐channel complexes which have properties like those of the native receptors in the muscle membrane.