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The structure of tandem regulatory regions in the deo operon of Escherichia coli K12
Author(s) -
ValentinHansen P.,
Aiba H.,
Schümperli D.
Publication year - 1982
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1002/j.1460-2075.1982.tb01167.x
Subject(s) - biology , operon , escherichia coli , escherichia coli proteins , genetics , tandem , computational biology , gene , materials science , composite material
The transcription initiation sites of the deo operon of Escherichia coli K12 have been determined in vitro and in vivo . Initiation of transcription occurs at two, tandemly arranged, homologous regions which are located 600 base pairs apart from each other. Evidence for a novel regulation mechanism of deo gene expression involving the deo R repressor is presented.