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The biofilm‐associated bacterial infections unrelated to indwelling devices
Author(s) -
Mirzaei Rasoul,
Mohammadzadeh Rokhsareh,
Alikhani Mohammad Yousef,
Shokri Moghadam Mohammad,
Karampoor Sajad,
Kazemi Sima,
Barfipoursalar Alireza,
Yousefimashouf Rasoul
Publication year - 2020
Publication title -
iubmb life
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.132
H-Index - 113
eISSN - 1521-6551
pISSN - 1521-6543
DOI - 10.1002/iub.2266
Subject(s) - biofilm , microbiology and biotechnology , tonsillitis , medicine , otitis , dental plaque , biology , antibiotics , immunology , bacteria , pathology , genetics , surgery
Biofilms are microbial communities established in the self‐produced extracellular substances that include up to 80% of associated microbial infections. During biofilm formation, bacterial cells shift from the planktonic forms to aggregated forms surrounded by an extracellular polymeric substance. The bacterial biofilm shows resistance against immune reactions as well as antibiotics and is potentially able to cause disorders by both device‐related and nondevice‐related infections. The nondevice‐related bacterial biofilm infections include dental plaque, urinary tract infections, cystic fibrosis, otitis media, infective endocarditis, tonsillitis, periodontitis, necrotizing fasciitis, osteomyelitis, infectious kidney stones, and chronic inflammatory diseases. In this review, we will summarize and examine the literature about bacterial biofilm infections unrelated to indwelling devices.