Open AccessDevelopment of male breast cancer in a patient with prostate cancer during androgen deprivation therapy
Author(s) -
Mizusawa Hiroya,
Komatsu Akira,
Mimura Yuji,
Maejima Toshitaka
Publication year - 2022
Publication title -
iju case reports
Language(s) - English
Resource type - Journals
ISSN - 2577-171X
DOI - 10.1002/iju5.12409
Subject(s) - medicine , breast cancer , male breast cancer , prostate cancer , androgen deprivation therapy , cancer , hormone therapy , oncology , hormonal therapy , prostate , lymph node , ca15 3
Introduction Male breast cancer accounts for <1% of all breast cancer. We report a patient with prostate cancer during hormone therapy who developed breast cancer. Case presentation An 88‐year‐old male underwent androgen deprivation therapy for prostate cancer and developed an induration in the left breast 7 years after the start of treatment. After close examination, he was diagnosed with left breast cancer with lymph node metastasis. The prostate cancer was stable in a hormone‐sensitive state. Left mastectomy was performed and the pathological diagnosis was invasive ductal carcinoma. Discussion In addition to our patient, seven patients who developed breast cancer during hormone therapy for prostate cancer were examined. Five of six patients had stage II or above, and four patients had lymph node metastases. Although local breast symptoms are frequently observed as adverse effects of hormone therapy, caution is warranted regarding male breast cancer.