Open AccessProstate carcinoma with neuroendocrine differentiation successfully treated by early detection with imaging examination
Author(s) -
Kobayashi Momoko,
Hagiwara Masahiro,
Yamashita Hideyuki,
Ohbu Makoto,
Irie Akira
Publication year - 2020
Publication title -
iju case reports
Language(s) - English
Resource type - Journals
ISSN - 2577-171X
DOI - 10.1002/iju5.12219
Subject(s) - neuroendocrine differentiation , medicine , prostate cancer , pathological , prostate , prostate carcinoma , carcinoma , prostatectomy , pca3 , pathology , neuroendocrine carcinoma , oncology , cancer
Clinicopathological features of neuroendocrine differentiation of prostate carcinoma have not been totally clarified yet. It is known to be associated with poor prognosis. Case presentation A patient with growing prostate‐specific antigen was diagnosed with prostate carcinoma and treated by laparoscopic prostatectomy. The pathological examination revealed the neuroendocrine differentiation of the tumor. Early detection of prostate carcinoma with neuroendocrine differentiation can be difficult due to its low expression of prostate‐specific antigen. The imaging examination contributed to the early detection. In the follow‐up period of 2 years, the patient remains cancer free. Conclusion Recently, the treatment options for prostate carcinoma have been expanded. Precise assessment of immunohistochemical nature of the tumor may be helpful for individualized decision‐making.