Open AccessRadiation‐induced sarcoma after radiation therapy for prostate adenocarcinoma
Author(s) -
Wakabayashi Kohei,
Konishi Kenta,
Komatsu Tetsuya,
Ishiba Ryo,
Ota Naofumi,
Ito Toshiki,
Aki Ryota,
Tsuchida Takashi,
Miyake Hideaki,
Nakamura Katsumasa
Publication year - 2019
Publication title -
iju case reports
Language(s) - English
Resource type - Journals
ISSN - 2577-171X
DOI - 10.1002/iju5.12052
Subject(s) - medicine , prostate cancer , radiation therapy , sarcoma , dysuria , prostate , radiology , cancer , soft tissue sarcoma , malignancy , adenocarcinoma , pathology , urinary system
Radiation therapy is widely used for prostate cancer, but radiation‐induced sarcomas have been rarely reported. Case presentation A 77‐year‐old Japanese male was diagnosed with prostate cancer and received a combined androgen blockade and radiation therapy (total dose of 76 Gy). Five years after the radiation therapy, testicular pain and dysuria appeared. Computed tomography showed a soft tissue dense mass with invasion to the right subpubic ramus and prostate, mainly to the perineum. A needle biopsy revealed the pathological features of high‐grade sarcoma. The patient was diagnosed with radiation‐induced sarcoma based on the cancer's occurrence in the vicinity of the radiation field. Conclusion Although irradiation is one of the important treatments for prostate cancer, the risk of radiation‐induced malignancy should be considered.