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Updated experience of a tertiary pandemic center on 533 pregnant women with COVID‐19 infection: A prospective cohort study from Turkey
Author(s) -
Sahin Dilek,
Tanacan Atakan,
Erol Seyit A.,
Anuk Ali T.,
Yetiskin Fatma D.Y.,
Keskin Huseyin L.,
Ozcan Namik,
OzguErdinc A. Seval,
Eyi Elif G.Y.,
Yucel Aykan,
Tayman Cuneyt,
Unlu Serpil,
Dinc Bedia,
Sari Eyup,
Surel Aziz A.,
Moraloglu Ozlem T.
Publication year - 2021
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1002/ijgo.13460
Subject(s) - medicine , covid-19 , pandemic , prospective cohort study , center (category theory) , tertiary care , cohort study , cohort , obstetrics , pregnancy , virology , family medicine , surgery , outbreak , infectious disease (medical specialty) , disease , biology , genetics , chemistry , crystallography
Objective To investigate the clinical course and impact of coronavirus disease 2019 (COVID‐19) infection on pregnant women. Methods A prospective cohort study was conducted on pregnant women with confirmed COVID‐19 infection. Demographic features, clinical characteristics, and perinatal outcomes were prospectively evaluated. Results Of the 533 cases, 161 (30.2%) had co‐morbidities and 165 (30.9%) were asymptomatic. Cough ( n = 178, 33.4%) and myalgia ( n = 168, 31.5%) were the leading symptoms. In total, 261 patients (48.9%) received COVID‐19 therapy, 509 (95.5%) had mild disease, 7 (1.3%) were admitted to the intensive care unit (ICU), and invasive mechanical ventilation was necessary in 2 (0.4%) patients. Maternal mortality was observed in 2 (0.4%) cases. Of the patients, 297 (55.7%) were hospitalized, 39 (7.3%) had suspicious radiologic imaging findings, 66 (12.4) had pregnancy complications (preterm delivery [ n =22, 4.1%] and miscarriage [ n =12, 2.2%] were the most common pregnancy complications), 131 births occurred, and the cesarean section rate was 66.4%. All neonates were negative for COVID‐19. The rate of admission to the neonatal ICU was 9.9%. One specimen of breast milk was positive for the infection. Conclusion The course of COVID‐19 was mild in the majority of cases. However, increased rates of pregnancy complications and cesarean delivery were observed.