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Comparison of the AV Magnivisualizer device with colposcopy to detect cervical intraepithelial neoplasia using the Swede scoring system
Author(s) -
Dayal Utkarsh,
Gupta Bindiya,
Hariprasad Roopa,
Shriya Rashmi,
Rajaram Shalini,
Prasad Bhavya,
Mehrotra Ravi
Publication year - 2019
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1002/ijgo.12931
Subject(s) - colposcopy , medicine , cervical intraepithelial neoplasia , receiver operating characteristic , gynecology , cervicitis , tertiary care , obstetrics , cervical cancer , surgery , cancer
Objective To compare the AV Magnivisualizer with colposcopy to detect cervical intraepithelial neoplasia ( CIN ) using the Swede scoring system. Methods Cross‐sectional study conducted in a tertiary care hospital from May 2017 to March 2018. One hundred women with positive results at visual inspection with acetic acid underwent cervical inspection using the Magnivisualizer followed by a colposcope. Biopsies were taken if the Swede score was greater than 4. Pregnant women, women with an obvious cervical growth, acute cervicitis, or prior cervical surgery were excluded. Diagnostic accuracy of the Magnivisualizer and colposcope was calculated for high‐grade lesions ( CIN 2/ CIN 2+) and agreement was compared between the two modalities. Results The sensitivity, specificity, and positive and negative predictive values of the Magnivisualizer were 88.2%, 70.0%, 50.0%, and 94.6%, respectively, to detect high‐grade lesions at a Swede score cutoff of 5 or more. The area under the curve for the Magnivisualizer was 0.80 (95% CI , 0.67–0.92), which was comparable with colposcopy ( AUC 0.86; 95% CI , 0.76–0.96). There was very good agreement between the Magnivisualizer and colposcopy (κ=0.865, P <0.001) for high‐grade lesions. Conclusion The Magnivisualizer had high diagnostic accuracy to detect high‐grade CIN in screen‐positive women, which was comparable with colposcopy.