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Prevalence of fibromyalgia among women with deep infiltrating endometriosis
Author(s) -
Coloma Jose Luis,
MartínezZamora MariaAngeles,
Collado Antonio,
Gràcia Meritxell,
Rius Mariona,
Quintas Lara,
Carmona Francisco
Publication year - 2019
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1002/ijgo.12822
Subject(s) - fibromyalgia , medicine , endometriosis , confidence interval , epidemiology , observational study , pelvic pain , physical therapy , gynecology , obstetrics , surgery
Objective To estimate the prevalence of fibromyalgia among women with endometriosis and analyze the effect of fibromyalgia on health‐related quality of life ( HRQ oL). Methods An observational case–control study conducted at a tertiary hospital in Barcelona between April 2015 and March 2017 among women with deep infiltrating endometriosis ( DIE ; n=80), women with superficial endometriosis or ovarian endometrioma (non‐ DIE ; n=76), and control women without endometriosis (n=73). Fibromyalgia was assessed via the London Fibromyalgia Epidemiological Study Screening Questionnaire ( LFESSQ ). HRQ oL was evaluated with the 36‐Item Short Form ( SF ‐36) questionnaire. The impact of fibromyalgia and other clinical characteristics was assessed by multivariate regression analysis. Results More women fulfilled the criteria for fibromyalgia in the DIE group than in the non‐ DIE and control groups by LFESSQ ‐4 (31 [39%], 12 [16%], and 6 [8%], respectively; P =0.009) and LFESSQ ‐6 (22 [28%], 8 [11%], and 4 [5%], respectively; P =0.008). The DIE group reported significantly poorer HRQ oL for all SF ‐36 dimensions. Women with DIE who fulfilled the criteria for fibromyalgia had lower physical component scores (−31.6; 95% confidence interval, −50.8 to −12.3; P =0.003). Conclusion The estimated prevalence of fibromyalgia was higher among women with DIE . Women with DIE and positive fibromyalgia screening had lower HRQ oL.