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The effects of hysterectomy with bilateral salpingectomy on ovarian reserve
Author(s) -
Yuan Zhen,
Cao Dongyan,
Bi Xiaoning,
Yu Mei,
Yang Jiaxin,
Shen Keng
Publication year - 2019
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1002/ijgo.12798
Subject(s) - ovarian reserve , salpingectomy , medicine , hysterectomy , anti müllerian hormone , gynecology , body mass index , follicle stimulating hormone , hormone , obstetrics , surgery , pregnancy , luteinizing hormone , infertility , ectopic pregnancy , genetics , biology
Objective To determine whether ovarian reserve is compromised after hysterectomy with bilateral salpingectomy. Methods A prospective longitudinal study was conducted among 84 women who underwent hysterectomy with bilateral salpingectomy at a tertiary medical center in Beijing, China, between August 2, 2015, and January 15, 2017. Serum levels of anti‐Müllerian hormone ( AMH ) and follicle‐stimulating hormone ( FSH ) were measured to assess ovarian function before undergoing the procedure (baseline) and at weeks 1 and 6 after surgery (postoperative period). Results The median age was 41.61 ± 0.62 years. Age negatively correlated with the serum AMH level at baseline ( P <0.001), as well as with preoperative‐to‐postoperative changes in the concentration of this hormone ( P <0.001). Serum AMH levels were lower in the postoperative period versus the preoperative period ( P <0.001). By contrast, serum FSH levels were higher in the postoperative period than in the preoperative period ( P <0.001). Moreover, no correlation was found with body mass index. Conclusions Hysterectomy with bilateral salpingectomy compromised ovarian reserve, with the damage being most severe among younger patients.