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Temporal changes in characteristics and outcomes among pregnant women with pre‐gestational diabetes
Author(s) -
Alessi Janine,
Wiegand Daniela M.,
Hirakata Vânia N.,
Oppermann Maria L.R.,
Reichelt Angela J.
Publication year - 2018
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1002/ijgo.12590
Subject(s) - medicine , gestational diabetes , pregnancy , type 2 diabetes , obstetrics , body mass index , diabetes mellitus , glycated hemoglobin , gestation , endocrinology , genetics , biology
Objective To evaluate pregnancy outcomes among women with pre‐gestational diabetes. Methods Retrospective analysis of pregnant women with type 1 or type 2 diabetes attending a university hospital in Brazil. Maternal characteristics and pregnancy outcomes were compared among deliveries between May 1, 2005, and December 31, 2010, and between January 1, 2011, and December 31, 2015. Risks were calculated by Poisson regression. Results In total 220 women were included. Type 1 diabetes was more frequent in 2005–2010 than in 2011–2015, and type 2 diabetes was more frequent in 2011–2015 ( P =0.005). History of macrosomia ( P =0.011), hypertensive disorders of pregnancy ( P =0.015), and pre‐gestational excess weight (body mass index >25 kg/m 2 ; P =0.003) was more frequent in 2011–2015. For women with type 1 diabetes, pre‐gestational weight ( P =0.007) and glycated hemoglobin ( P =0.026) were higher in 2011–2015. For women with type 2 diabetes, previous hypertensive disorders of pregnancy ( P =0.032) were more prevalent and family history of diabetes ( P <0.001) less prevalent in 2011–2015. Adverse pregnancy outcomes were similar for type 1 and type 2, and across both periods. Conclusion Type 2 diabetes became more common over the two time periods and women with type 1 diabetes had higher pre‐gestational weight. Perinatal outcomes were similar.