Premium
Comparative analysis of early adverse events of pelvic organ prolapse repair with or without transvaginal mesh using Clavien‐Dindo classification
Author(s) -
Besser Limor,
Schwarzman Polina,
Mastrolia Salvatore A.,
Rotem Reut,
Leron Elad,
Yohay David,
Weintraub Adi Y.
Publication year - 2018
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1002/ijgo.12501
Subject(s) - medicine , perioperative , adverse effect , surgery , native tissue , retrospective cohort study , urinary incontinence , odds ratio , surgical mesh , hernia , tissue engineering , biomedical engineering
Objective To assess adverse events following surgical repair of pelvic organ prolapse ( POP ) with or without the use of transvaginal mesh. Methods The present retrospective study was conducted among women who underwent surgical POP repair at Soroka University Medical Center, Beer Sheva, Israel, between January 1, 2013, and December 31, 2015. Patients underwent anterior and posterior colporrhaphy either with transvaginal mesh (Elevate Prolapse Repair System; American Medical Systems, Minnetonka, MN , USA ) or without transvaginal mesh (native tissue repair). Perioperative adverse events were assessed using the Clavien‐Dindo classification; multivariate regression models were constructed to predict minor and major adverse events. Results There were 111 women included; 35 were treated with transvaginal mesh, and 76 underwent native tissue repair. Women undergoing native tissue repair had a lower mean grade of cystocele ( P =0.023) and a higher rate of urinary stress incontinence ( P =0.017) than patients treated with transvaginal mesh. The duration of surgery ( P =0.002), duration of hospitalization ( P <0.001), and the amount of blood loss ( P =0.021) were lower in the native tissue repair group. Repair with transvaginal mesh was not associated with increased odds of major or minor adverse events ( P >0.05 for all models examined). Conclusion Perioperative and postoperative adverse events were comparable regardless of the operative approach.