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Association between maternal vascular murmur and the small‐for‐gestational‐age fetus with abnormal umbilical artery Doppler flow
Author(s) -
Riknagel Diana,
Farlie Richard,
Hedegaard Morten,
Humaidan Peter,
Struijk Johannes J.
Publication year - 2017
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1002/ijgo.12268
Subject(s) - medicine , small for gestational age , fetus , intrauterine growth restriction , obstetrics , gestational age , pregnancy , umbilical artery , uterine artery , cardiology , gestation , genetics , biology
Abstract Objective To investigate the association between maternal vascular murmurs ( MVM s) and fetal growth restriction (defined as small‐for‐gestational‐age [ SGA ] fetus) and abnormal Doppler pulsatility index ( PI ) of the uterine and/or umbilical arteries. Methods A cross‐sectional study of women aged 18 years or older with a singleton pregnancy at 28–34 weeks was conducted at Regional Hospital Viborg, Denmark, between May 1 and August 1, 2013. Ultrasound fetal biometry was performed and the Doppler PI of the umbilical and uterine arteries was determined. An estimated fetal weight ( EFW ) at or below the 10th percentile was defined as SGA . Microphone recordings from the lower abdomen were divided into heart valve sounds and MVM s. Results The final analysis included 63 participants, with 25 classified as SGA and 38 as non‐ SGA . The mean pregnancy duration was 32.4 ± 1.4 weeks. In total, 17 participants had MVM s. There was a clear association between MVM s and a composite of SGA and an abnormal PI of the uterine and/or the umbilical artery ( P< 0.001), but not between MVM s and SGA only ( P= 0.154). Conclusion Maternal vascular murmurs are significantly associated with fetal growth restriction, but not with SGA per se.