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The effect of prophylactic antibiotic treatment for manual removal of the placenta on frequency of postpartum endometritis
Author(s) -
Safrai Myriam,
Kabiri Doron,
HajYahya Rani,
ReuveniSalzman Adi,
Lipschuetz Michal,
Ezra Yossef
Publication year - 2017
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1002/ijgo.12254
Subject(s) - endometritis , medicine , odds ratio , retained placenta , obstetrics , antibiotics , postpartum period , confidence interval , retrospective cohort study , gynecology , pregnancy , placenta , fetus , genetics , microbiology and biotechnology , biology
Objective To determine whether prophylactic antibiotics reduce the frequency of postpartum endometritis after manual removal of the placenta. Methods A retrospective cohort study was conducted using data for all women who underwent manual removal of the placenta after vaginal delivery at a tertiary medical center in Jerusalem, Israel, between January 1, 2010, and December 31, 2015. The study group comprised women who had not received prophylactic antibiotic treatment, whereas the control group comprised women who had received prophylactic antibiotic treatment. The primary outcome measure was the frequency of postpartum endometritis. Results Of the 407 women included in the analysis, 7 (1.7%) developed postpartum endometritis. Six of the women with postpartum endometritis had received prophylactic treatment with antibiotics, whereas one woman had not (odds ratio 0.555, 95% confidence interval 0.065–4.630). Conclusion Prophylactic antibiotics before manual removal of the placenta did not decrease the odds of postpartum endometritis.