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Doppler assessment of patients with twin‐to‐twin transfusion syndrome and survival following fetoscopic laser surgery
Author(s) -
Gil Guevara Enrique,
Pazos Andrea,
Gonzalez Otilia,
Carretero Pilar,
Molina Francisca S.
Publication year - 2017
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1002/ijgo.12143
Subject(s) - ductus venosus , medicine , fetus , twin twin transfusion syndrome , fetoscopy , laser surgery , retrospective cohort study , survival rate , fetal surgery , laser doppler velocimetry , surgery , obstetrics , pregnancy , prenatal diagnosis , cardiology , blood flow , in utero , laser , genetics , physics , optics , biology
Objective To investigate fetal‐survival rates following laser surgery for twin‐to‐twin transfusion syndrome ( TTTS ) and the impact of Doppler analysis. Methods The present retrospective single‐center study included data from patients with pregnancies exhibiting TTTS treated with fetoscopic laser surgery between January 1, 2007, and December 31, 2016. Perinatal outcomes were examined and variables were compared between the donor and recipient fetuses that survived and died, respectively. Results There were 86 pregnancies exhibiting TTTS treated with fetoscopic laser surgery included in the study. The median length of pregnancy at the time of surgery was 21.1 weeks. Both twin fetuses and at least one fetus survived in 61 (71%) and 73 (85%) pregnancies, respectively. Among recipient fetuses, ductus venosus a‐wave anomalies ( P =0.026), shorter cervical length ( P =0.044), and a greater than 25% discrepancy in the estimated weight of the twin fetuses ( P =0.045) were associated with reduced survival. Conclusion Among pregnancies exhibiting TTTS , laser surgery was associated with significant dual‐fetus survival. Preoperative ductus venosus anomalies were associated with lower survival among recipient fetuses, and 1‐week postsurgical ultrasonography data demonstrated lower survival among recipient fetuses with persistent anomalous ductus venosus compared with normalized ductus venosus.