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Association of previous severe low birth weight with adverse perinatal outcomes in a subsequent pregnancy among HIV ‐prevalent urban African women
Author(s) -
Smid Marcela C.,
Ahmed Yusuf,
Stoner Marie C.D.,
Vwalika Bellington,
Stringer Elizabeth M.,
Stringer Jeffrey S.A.
Publication year - 2017
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1002/ijgo.12040
Subject(s) - medicine , low birth weight , odds ratio , obstetrics , pregnancy , birth weight , confidence interval , population , premature birth , retrospective cohort study , cohort study , adverse effect , pediatrics , gestational age , environmental health , genetics , biology
Objective To evaluate the association between severity of prior low birth weight ( LBW ) delivery and adverse perinatal outcomes in the subsequent delivery among an HIV ‐prevalent urban African population. Methods A retrospective cohort study was conducted among 41 109 women who had undergone two deliveries in Lusaka, Zambia, between February 1, 2006, and May 31, 2013. The relationship between prior LBW delivery (<2500 g) and a composite measure of adverse perinatal outcome in the second pregnancy was assessed using multivariate logistic regression. Results Women with prior LBW delivery (n=4259) had an increased risk of LBW in the second delivery versus those without prior LBW delivery (n=37 642). Such risk correlated with the severity of first delivery LBW . The adjusted odds ratio ( AOR ) was 2.89 (95% confidence interval [ CI ] 2.05–4.09) for a birth weight of 1000–1499 g, 3.05 (95% CI 2.42–3.86) for a birth weight of 1500–1999 g, and 2.02 (95% CI 1.81–2.27) for a birth weight of 2000–2499 g. Previous LBW delivery also increased the risk of adverse perinatal outcome, with an AOR of 1.4 (95% CI 1.2–1.7). Conclusion Severe prior LBW delivery conferred substantial risk for adverse perinatal outcomes in a subsequent pregnancy.