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Buchwald‐Type Ligands on Gold(I) Catalysis
Author(s) -
Zuccarello Giuseppe,
Zanini Margherita,
Echavarren Antonio M.
Publication year - 2020
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.201900179
Subject(s) - chemistry , catalysis , enantioselective synthesis , ligand (biochemistry) , combinatorial chemistry , context (archaeology) , coupling reaction , nanotechnology , organic chemistry , receptor , paleontology , biochemistry , materials science , biology
Dialkyl biarylphosphine ligands, presented in the context of Pd‐catalyzed cross‐coupling reactions, have been extensively applied in gold(I) catalysis giving rise to numerous transformations and reaction pathways otherwise inaccessible under the action of other gold(I) catalysts. This review emphasizes how this privileged ligand class, as well as recent modifications on the biarylphosphine motive, have triggered the discovery of new reactivities in our research program. Finally, the introduction of chiral information on the ligand scaffold provides new solutions to challenging gold(I)‐catalyzed enantioselective transformations.