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Transition‐Metal‐Catalyzed 1,2‐Carboboration of Alkenes: Strategies, Mechanisms, and Stereocontrol
Author(s) -
Liu Zhen,
Gao Yang,
Zeng Tian,
Engle Keary M.
Publication year - 2020
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.201900087
Subject(s) - chemistry , catalysis , transition metal , scope (computer science) , combinatorial chemistry , organic chemistry , computer science , programming language
During the past decade, many research groups have described catalytic methods for 1,2‐carboboration, allowing access to structurally complex organoboronates from alkenes. Various transition metals, especially copper, palladium, and nickel, have been widely used in these reactions. This review summarizes advances in this field, with a special focus on the catalytic cycles involved in different metal‐catalyzed carboboration reactions, as well as the regio‐ and stereochemical consequences of the underlying mechanisms. 1,2‐Carboboration of other unsaturated systems, such as alkynes and allenes, is outside of the scope of this review.