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C 3 ‐Symmetrical π‐Scaffolds: Useful Building Blocks to Construct Helical Supramolecular Polymers
Author(s) -
Dorca Yeray,
Matern Jonas,
Fernández Gustavo,
Sánchez Luis
Publication year - 2019
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.201900017
Subject(s) - supramolecular chemistry , chemistry , isodesmic reaction , stereocenter , covalent bond , polymerization , side chain , chirality (physics) , supramolecular polymers , polymer , self assembly , molecule , nanotechnology , supramolecular chirality , materials science , organic chemistry , enantioselective synthesis , chiral symmetry breaking , physics , quantum mechanics , quark , nambu–jona lasinio model , catalysis
In this review, we highlight some relevant examples of C 3 ‐symmetrical molecules that have been reported to form supramolecular polymers and helical aggregates. In particular, the number and type of non‐covalent forces are key to bias the supramolecular polymerization leading from a simple isodesmic or cooperative mechanism to a more complex self‐assembly process, i. e. pathway complexity. Furthermore, the attachment of stereogenic centres at the peripheral side chains of the C 3 ‐systems provokes efficient transfer and amplification of chirality phenomena when directional and specific non‐covalent interactions operate. Interestingly, the incorporation of hydrophilic side chains induces the formation of organized aggregates in aqueous media with potential biomedical applications. Overall, the examples shown in this review on C 3 ‐symmetrical scaffolds illustrate the relevance of this molecular shape in the development of functional supramolecular structures.