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Polysaccharide Based Nanoparticles
Author(s) -
Khan Wahid,
Abtew Ester,
Modani Sheela,
Domb Abraham J.
Publication year - 2018
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.201800051
Subject(s) - pullulan , chemistry , chitosan , polysaccharide , biocompatibility , drug delivery , dextran , nanoparticle , nanotechnology , hyaluronic acid , organic chemistry , materials science , biology , genetics
Nanoparticles made of biodegradable polymers have outstanding merits as a drug delivery system. Polysaccharide‐based nanoparticles have been well explored because of their safety, stability, biocompatibility, biodegradability and hydrophilicity. The present review emphasizes the efforts articulated to improve polysaccharide‐based nanoparticles as drug delivery tool for effective therapy and site‐specific targeting of mainly anticancer agents. This review updates reports of recent research on polysaccharides‐based systems particularly chitosan, alginate, cyclodextrins, hyaluronic acid, pullulan, dextran and their combinations with potential applications.