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Recent Advances of Novel Proteinoids and Proteinoid Nanoparticles and Their Applications in Biomedicine and Industrial Uses
Author(s) -
KolitzDomb Michal,
Margel Shlomo
Publication year - 2018
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.201800021
Subject(s) - chemistry , nanotechnology , biomedicine , biocompatibility , nanoparticle , polymer , scope (computer science) , organic chemistry , computer science , materials science , bioinformatics , biology , programming language
Proteinoids, thermal polymers composed of amino acids, discovered and studied by Fox, spontaneously self‐assemble in spherical structures, microspheres, which Fox presented as the protocells of life. Fox's findings opened up a scope of applicable easy‐to‐make protein‐like particles. In recent years, interest in proteinoids has increased among nanobiomedicine research workers. These structures are suitable for biomedical applications, due to their protein‐like nature, biocompatibility, non‐toxicity and safety. Several new proteinoids made of a specific selection of amino acids were introduced for biomedical and agricultural industries. Several proteinoids include specific additives polymerized within their backbone, providing special chracteristics for a specific application. These proteinoids, their corresponding nanoparticles and their diverse applications are presented here, primarily focusing on proteinoids for cancer diagnostics and therapy, cosmetic and anti‐fog proteinoids.