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Hemicucurbit[ n ]urils and Their Derivatives – Synthesis and Applications
Author(s) -
Andersen Nicolaj N.,
Lisbjerg Micke,
Eriksen Kristina,
Pittelkow Michael
Publication year - 2018
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.201700129
Subject(s) - supramolecular chemistry , chemistry , nanotechnology , combinatorial chemistry , organic chemistry , molecule , materials science
The first hemicucurbit[ n ]uril macrocycles were described in 2004, and since then a series of functionalised hemicucurbit[ n ]uril derivatives have been prepared and studied. The original hemicucurbit[ n ]urils suffer from sparse solubility, which limits their applications in supramolecular chemistry. Recent progress in the synthesis of a range of derivatives such as the biotin[ n ]urils, the bambus[ n ]urils, and the cyclohexylhemicucurbit[ n ]urils have enabled studies of the supramolecular chemistry of the hemicucurbituril system, both in water and in a range of organic solvents. In contrast to the popular cucurbit[ n ]uril macrocycles that are state‐of‐the‐art hosts for cations, the hemicucbit[ n ]urils host anions. Herein we provide a survey of the literature covering the syntheses of the hemicucurbituril derivatives and their supramolecular chemistry.