Alkane Carbon‐Hydrogen Bond Functionalization as a Tool Toward a Steric Parameter for Hydrotris(pyrazolyl)borate (Tp x ) Ligands | Zendy

Caballero Ana | Zendy; Pérez Pedro J. | Zendy

Premium

Alkane Carbon‐Hydrogen Bond Functionalization as a Tool Toward a Steric Parameter for Hydrotris(pyrazolyl)borate (Tp x ) Ligands

Author(s) -

Caballero Ana,

Pérez Pedro J.

Publication year - 2017

Publication title -

israel journal of chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.908

H-Index - 54

eISSN - 1869-5868

pISSN - 0021-2148

DOI - 10.1002/ijch.201700110

Subject(s) - chemistry , steric effects , regioselectivity , surface modification , olefin fiber , alkane , catalysis , boron , ethyl diazoacetate , cyclopropanation , hydrogen bond , medicinal chemistry , organic chemistry , molecule

The effect of a series of hydrotris(pyrazolyl)borate ligands (Tp x ) in the regioselectivity of the catalytic functionalization of the secondary carbon‐hydrogen bonds of hexane with ethyl diazoacetate and Tp x CuL as the catalysts has led to the definition of the relative steric parameter SP R . The validity of the parameter has been assessed upon its correlation with the regioselectivity observed in several transformations (olefin cyclopropanation, C−H functionalization, C−H amidation), in all cases a good degree of fitting being observed.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research